Current advances in remote monitoring and treatment for populations (i.e., Smart Health) and in significantly improved agriculture through targeted application of fertilizer and pesticides (i.e., Smart Food) illustrate how biological systems inform Smart Living. Understanding and using Big Data related to climate change and a growing industrial base ties Smart Living to environmental sustainability. And new smart materials can turn buildings into “living laboratories” that, through advanced analytics, provide feedback to inform users as well as to adapt to human behavior.